Tm7sf2 - transmembrane 7 superfamily member 2 Gene

Also Known as ANG1; C14SR; Dhcr14; 3110041O18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73166

Summary

Enables delta14-sterol reductase activity. Involved in Cholesterol biosynthetic process. Located in organelle membrane. Is expressed in several structures, including adrenal gland; alimentary system; eye; liver; and nervous system. Orthologous to human TM7SF2 (transmembrane 7 superfamily member 2). [provided by Alliance of Genome Resources, Apr 2022]

Tm7sf2 Products (1)

mRNA Protein Name
NM_028454.2 NP_082730.2 delta(14)-sterol reductase TM7SF2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables delta14-sterol reductase activity IMP
IMP: Inferred from mutant phenotype
18785926 MGI
Biological Process GO Annotation Evidence References Source
involved in cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
18785926 MGI
Cellular Component GO Annotation Evidence References Source
located in organelle membrane IDA
IDA: Inferred from direct assay
18785926 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta(14)-sterol reductase TM7SF2

  • 3-beta-hydroxysterol Delta (14)-reductase

  • C-14 sterol reductase

  • delta-14-SR

  • sterol C14-reductase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14612 TM7SF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tm7sf2 NCBI NCBI:7108