Bmper - BMP-binding endothelial regulator Gene

Also Known as Cv2; CV-2; Crim3; 3110056H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73230

Summary

This gene encodes a secreted protein that contains five Von Willebrand factor type C domains and a Von Willebrand factor type D domain and a trypsin inhibitory-like domain. The encoded protein binds to bone morphogenetic proteins (BMP) and regulates their activity. Mutation of the related gene in humans causes diaphanospondylodysostosis. [provided by RefSeq, Mar 2013]

Bmper Products (1)

mRNA Protein Name
NM_028472.2 NP_082748.1 BMP-binding endothelial regulator protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
12897139 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in BMP signaling pathway IMP
IMP: Inferred from mutant phenotype
20807528 MGI
involved in SMAD protein signal transduction IMP
IMP: Inferred from mutant phenotype
20807528 MGI
acts upstream of or within inner ear development IDA
IDA: Inferred from direct assay
21795542 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
12897139 MGI
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
20807528 MGI
involved in ureteric bud development IEP
IEP: Inferred from expression pattern
16545622 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular region IDA
IDA: Inferred from direct assay
12897139 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BMP-binding endothelial regulator protein

  • bone morphogenetic protein-binding endothelial cell precursor-derived regulator

  • crossveinless-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01545 BMPER Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bmper NCBI NCBI:168667