Marveld3 - MARVEL (membrane-associating) domain containing 3 Gene

Also Known as Marvd3; Mrvldc3; 1810006A16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73608

Summary

Predicted to enable mitogen-activated protein kinase kinase kinase binding activity. Acts upstream of or within cell-cell junction organization; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Located in bicellular tight junction. Is expressed in brain ventricle and choroid plexus; foregut; renal calyx; retina; and trachea. Orthologous to human MARVELD3 (MARVEL domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Marveld3 Products (2)

mRNA Protein Name
NM_028584.3 NP_082860.2 MARVEL domain-containing protein 3 isoform a
NM_212447.2 NP_997612.2 MARVEL domain-containing protein 3 isoform b
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell-cell junction organization IMP
IMP: Inferred from mutant phenotype
20164257 MGI
acts upstream of or within negative regulation of epithelial cell migration IDA
IDA: Inferred from direct assay
24567356 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
24567356 MGI
Cellular Component GO Annotation Evidence References Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
20164257 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MARVEL domain-containing protein 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Marveld3 NCBI NCBI:91862