Tubb2b - tubulin, beta 2B class IIB Gene

Also Known as brdp; 2410129E14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73710

Summary

Predicted to enable GTP binding activity and protein heterodimerization activity. Predicted to be a structural constituent of Cytoskeleton. Involved in modulation of chemical synaptic transmission. Acts upstream of or within embryonic brain development. Located in Schaffer collateral - CA1 synapse. Is expressed in several structures, including brain; large intestine; lung; sensory organ; and thymus. Used to study complex cortical dysplasia with Other brain malformations 7. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb). [provided by Alliance of Genome Resources, Apr 2022]

Tubb2b Products (1)

mRNA Protein Name
NM_023716.2 NP_076205.1 tubulin beta-2B chain

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cerebral cortex development IMP
IMP: Inferred from mutant phenotype
31386652 MGI
acts upstream of or within embryonic brain development IMP
IMP: Inferred from mutant phenotype
21515572 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
27594048 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
27594048 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
27594048 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
27594048 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-2B chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15253 TUBB2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb2b NCBI NCBI:347733