Rbm20 - RNA binding motif protein 20 Gene

Also Known as 1110018J23Rik; 2010003H22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73713

Summary

Enables RNA binding activity. Involved in positive regulation of RNA splicing. Located in nucleus. Is expressed in diaphragm; heart; limb segment; skeletal musculature; and tail paraxial mesenchyme. Used to study atrial fibrillation and dilated cardiomyopathy 1DD. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1DD. Orthologous to human RBM20 (RNA binding motif protein 20). [provided by Alliance of Genome Resources, Apr 2022]

Rbm20 Products (1)

mRNA Protein Name
NM_001170847.1 NP_001164318.1 RNA-binding protein 20

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
22466703 MGI
enables pre-mRNA intronic binding IDA
IDA: Inferred from direct assay
32187365 MGI
Biological Process GO Annotation Evidence References Source
involved in heart formation IMP
IMP: Inferred from mutant phenotype
24584570 MGI
involved in negative regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
27630136 MGI
involved in positive regulation of RNA splicing IMP
IMP: Inferred from mutant phenotype
22466703 MGI
involved in spliceosome-depend formation of circular RNA IDA
IDA: Inferred from direct assay
37272356 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic ribonucleoprotein granule IDA
IDA: Inferred from direct assay
35041844 MGI
is active in nucleus IDA
IDA: Inferred from direct assay
23886709 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22466703 MGI
is active in nucleus IMP
IMP: Inferred from mutant phenotype
33110103 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein 20

  • probable RNA-binding protein 20

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11739 RBM20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbm20 NCBI NCBI:282996