2. Gene
  3. Mfsd12 - major facilitator superfamily domain containing 12 Gene

Mfsd12 - major facilitator superfamily domain containing 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as gr; Wdt1; C19orf28; F630110N24Rik

Gene ID: 73822 | Gene type: protein coding

About Mfsd12

Summary

Predicted to enable cysteine transmembrane transporter activity. Involved in negative regulation of melanin biosynthetic process and pigment metabolic process involved in pigmentation. Acts upstream of or within hair follicle development and pigmentation. Predicted to be located in late endosome; lysosome; and melanosome. Predicted to be integral component of plasma membrane. Is expressed in thymus primordium. Orthologous to human MFSD12 (major facilitator superfamily domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

Mfsd12 Products(1)

mRNA Protein Name
NM_028657.4 NP_082933.2 major facilitator superfamily domain-containing protein 12
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
29025994 MGI
involved in pigment metabolic process involved in pigmentation IMP
IMP: Inferred from mutant phenotype
33208952 MGI
involved in regulation of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
33208952 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

major facilitator superfamily domain-containing protein 12

protein grizzled

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08390 MFSD12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfsd12 NCBI NCBI:126321