Arsg - arylsulfatase G Gene

Also Known as ASG; 6330406P08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74008

Summary

Enables N-sulfoglucosamine-3-sulfatase activity and arylsulfatase activity. Predicted to be involved in sulfur compound metabolic process. Located in lysosome. Is expressed in central nervous system and retina. Used to study mucopolysaccharidosis. Human ortholog(s) of this gene implicated in Usher syndrome. Orthologous to human ARSG (arylsulfatase G). [provided by Alliance of Genome Resources, Apr 2022]

Arsg Products (5)

mRNA Protein Name
NM_001166177.1 NP_001159649.1 arylsulfatase G isoform 2
NM_001361975.1 NP_001348904.1 arylsulfatase G isoform 1 precursor
NM_001361977.1 NP_001348906.1 arylsulfatase G isoform 3
NM_001361978.1 NP_001348907.1 arylsulfatase G isoform 4
NM_028710.3 NP_082986.3 arylsulfatase G isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-sulfoglucosamine-3-sulfatase activity IMP
IMP: Inferred from mutant phenotype
22689975 MGI
enables arylsulfatase activity IDA
IDA: Inferred from direct assay
25135642 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
26975023 MGI
acts upstream of or within glial cell differentiation IMP
IMP: Inferred from mutant phenotype
26975023 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: Inferred from mutant phenotype
26975023 MGI
acts upstream of or within lysosome organization IMP
IMP: Inferred from mutant phenotype
26975023 MGI
acts upstream of or within neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
26975023 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
26975023 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
25135642 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase G

  • N-sulfoglucosamine-3-sulfatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01038 ARSG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsg NCBI NCBI:22901