Tmem43 - transmembrane protein 43 Gene

Also Known as LUMA; 1200015A22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74122

Summary

Enables protein self-association. Acts upstream of or within nuclear membrane organization. Located in endoplasmic reticulum lumen and nuclear inner membrane. Is integral component of nuclear inner membrane. Is expressed in several structures, including aorta; cartilage; future spinal cord; genitourinary system; and oral epithelium. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 5; and autosomal dominant Emery-Dreifuss muscular dystrophy 7. Orthologous to human TMEM43 (transmembrane protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Tmem43 Products (1)

mRNA Protein Name
NM_028766.3 NP_083042.1 transmembrane protein 43

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
18230648 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within nuclear membrane organization IDA
IDA: Inferred from direct assay
18230648 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
18230648 MGI
located in nuclear inner membrane IDA
IDA: Inferred from direct assay
18230648 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 43

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14724 TMEM43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem43 NCBI NCBI:79188