2. Gene
  3. Sipa1l3 - signal-induced proliferation-associated 1 like 3 Gene

Sipa1l3 - signal-induced proliferation-associated 1 like 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2610511M17Rik

Gene ID: 74206 | Gene type: protein coding

About Sipa1l3

Summary

Predicted to enable GTPase activator activity. Involved in several processes, including epithelial cell morphogenesis; establishment of epithelial cell polarity; and eye development. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in several cellular components, including nucleoplasm; stress fiber; and tricellular tight junction. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in lens vesicle. Human ortholog(s) of this gene implicated in cataract 45. Orthologous to human SIPA1L3 (signal induced proliferation associated 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]

Sipa1l3 Products(1)

mRNA Protein Name
NM_001081028.1 NP_001074497.1 signal-induced proliferation-associated 1-like protein 3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
26231217 MGI
involved in epithelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
26231217 MGI
involved in establishment of epithelial cell polarity IMP
IMP: Inferred from mutant phenotype
26231217 MGI
involved in eye development IMP
IMP: Inferred from mutant phenotype
26231217 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

signal-induced proliferation-associated 1-like protein 3

SIPA1-like protein 3

SPA-1-like protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12931 SIPA1L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sipa1l3 NCBI NCBI:23094