Mettl23 - methyltransferase like 23 Gene

Also Known as 1110005A03Rik; 1500035B17Rik; 4933424L15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74319

Summary

Predicted to enable DNA-binding transcription factor binding activity and heat shock protein binding activity. Predicted to be involved in cognition and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within methylation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in embryo. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human METTL23 (methyltransferase like 23). [provided by Alliance of Genome Resources, Apr 2022]

Mettl23 Products (1)

mRNA Protein Name
NM_028865.3 NP_083141.3 histone-arginine methyltransferase METTL23

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone H3R17 methyltransferase activity IDA
IDA: Inferred from direct assay
28930672 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28930672 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of positive effect epigenetic programing of male pronucleus IMP
IMP: Inferred from mutant phenotype
28930672 MGI
involved in epigenetic programming in the zygotic pronuclei IMP
IMP: Inferred from mutant phenotype
28930672 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28930672 MGI
located in female pronucleus IDA
IDA: Inferred from direct assay
28930672 MGI
is active in male pronucleus IDA
IDA: Inferred from direct assay
28930672 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-arginine methyltransferase METTL23

methyltransferase-like protein 23

  • probable methyltransferase-like protein 23

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08362 METTL23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mettl23 NCBI NCBI:124512