Lrrtm1 - leucine rich repeat transmembrane neuronal 1 Gene

Also Known as 4632401D06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74342

Summary

Acts upstream of or within several processes, including long-term synaptic potentiation; negative regulation of receptor internalization; and positive regulation of synapse assembly. Predicted to be located in endoplasmic reticulum; excitatory synapse; and growth cone. Predicted to be integral component of membrane. Predicted to be active in GABA-ergic synapse; extracellular matrix; and extracellular space. Predicted to be integral component of postsynaptic specialization membrane. Is expressed in several structures, including central nervous system; future brain; limb; peripheral nervous system; and sensory organ. Used to study schizophrenia. Orthologous to human LRRTM1 (leucine rich repeat transmembrane neuronal 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrrtm1 Products (2)

mRNA Protein Name
NM_001362109.1 NP_001349038.1 leucine-rich repeat transmembrane neuronal protein 1 precursor
NM_028880.4 NP_083156.2 leucine-rich repeat transmembrane neuronal protein 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of establishment of localization in cell IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within exploration behavior IMP
IMP: Inferred from mutant phenotype
23089646 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
21818371 MGI
acts upstream of or within long-term synaptic potentiation IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within negative regulation of receptor internalization IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within protein localization to synapse IMP
IMP: Inferred from mutant phenotype
19285470 MGI
acts upstream of receptor internalization IGI
IGI: Inferred from genetic interaction
23931994 MGI
acts upstream of or within synapse organization IGI
IGI: Inferred from genetic interaction
21788371 MGI
acts upstream of or within synapse organization IMP
IMP: Inferred from mutant phenotype
19285470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane neuronal protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07841 LRRTM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrtm1 NCBI NCBI:347730