Neto2 - neuropilin (NRP) and tolloid (TLL)-like 2 Gene

Mus musculus

Also known as BTCL2; 5530601C23Rik

Gene ID: 74513 | Gene type: protein coding

About Neto2

Summary

Enables ionotropic glutamate receptor binding activity. Predicted to be involved in regulation of kainate selective glutamate receptor activity. Located in postsynaptic density. Is expressed in central nervous system and retina. Orthologous to human NETO2 (neuropilin and tolloid like 2). [provided by Alliance of Genome Resources, Apr 2022]

Neto2 Products(3)

mRNA	Protein	Name
NM_001081324.2	NP_001074793.1	neuropilin and tolloid-like protein 2 isoform 3
NM_001357287.1	NP_001344216.1	neuropilin and tolloid-like protein 2 isoform 1 precursor
NM_001357288.1	NP_001344217.1	neuropilin and tolloid-like protein 2 isoform 2 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ionotropic glutamate receptor binding	IPI IPI: Inferred from physical interaction	21734292	MGI

Biological Process GO Annotation	Evidence	Reference	Source
NOT acts upstream of or within positive regulation of excitatory postsynaptic potential	IMP IMP: Inferred from mutant phenotype	21734292	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	23236500	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	23236500	MGI
located in postsynaptic density	IDA IDA: Inferred from direct assay	21734292	MGI
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	23236500	MGI
is active in postsynaptic density membrane	IEP IEP: Inferred from expression pattern	23236500	MGI
located in synapse	IDA IDA: Inferred from direct assay	21734292	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

neuropilin and tolloid-like protein 2

brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09214	NETO2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Neto2	NCBI	NCBI:81831

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