Neto2 - neuropilin (NRP) and tolloid (TLL)-like 2 Gene

Also Known as BTCL2; 5530601C23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74513

Summary

Enables ionotropic glutamate receptor binding activity. Predicted to be involved in regulation of kainate selective glutamate receptor activity. Located in postsynaptic density. Is expressed in central nervous system and retina. Orthologous to human NETO2 (neuropilin and tolloid like 2). [provided by Alliance of Genome Resources, Apr 2022]

Neto2 Products (3)

mRNA Protein Name
NM_001081324.2 NP_001074793.1 neuropilin and tolloid-like protein 2 isoform 3
NM_001357287.1 NP_001344216.1 neuropilin and tolloid-like protein 2 isoform 1 precursor
NM_001357288.1 NP_001344217.1 neuropilin and tolloid-like protein 2 isoform 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
21734292 MGI
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within positive regulation of excitatory postsynaptic potential IMP
IMP: Inferred from mutant phenotype
21734292 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23236500 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
23236500 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
21734292 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
23236500 MGI
is active in postsynaptic density membrane IEP
IEP: Inferred from expression pattern
23236500 MGI
located in synapse IDA
IDA: Inferred from direct assay
21734292 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuropilin and tolloid-like protein 2

  • brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09214 NETO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neto2 NCBI NCBI:81831