2. Gene
  3. Wdr35 - WD repeat domain 35 Gene

Wdr35 - WD repeat domain 35 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1336; 4931430C06; 4930459M12Rik

Gene ID: 74682 | Gene type: protein coding

About Wdr35

Summary

Involved in cilium assembly. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in axoneme; centrosome; and ciliary basal body. Part of intraciliary transport particle A. Is expressed in several structures, including choroid plexus; limb mesenchyme; lobar bronchus epithelium; metanephros; and sensory organ. Used to study short-rib thoracic dysplasia 7 with or without polydactyly. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35). [provided by Alliance of Genome Resources, Apr 2022]

Wdr35 Products(2)

mRNA Protein Name
NM_001159527.1 NP_001152999.1 WD repeat-containing protein 35 isoform 2
NM_172470.3 NP_766058.3 WD repeat-containing protein 35 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
21473986 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axoneme IDA
IDA: Inferred from direct assay
21473986 MGI
located in centrosome IDA
IDA: Inferred from direct assay
21473986 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
21473986 MGI
part of intraciliary transport particle A IDA
IDA: Inferred from direct assay
20889716 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat-containing protein 35

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15774 WDR35 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdr35 NCBI NCBI:57539