Stx11 - syntaxin 11 Gene

Also Known as 5830405C08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74732

Summary

Predicted to enable SNAP receptor activity and SNARE binding activity. Acts upstream of or within cellular response to interferon-gamma and leukocyte degranulation. Located in phagocytic vesicle. Is expressed in femur; fibula; humerus; scapula; and tibia. Used to study familial hemophagocytic lymphohistiocytosis 4. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 4. Orthologous to human STX11 (syntaxin 11). [provided by Alliance of Genome Resources, Apr 2022]

Stx11 Products (3)

mRNA Protein Name
NM_001163590.1 NP_001157062.1 syntaxin-11
NM_001163591.1 NP_001157063.1 syntaxin-11
NM_029075.1 NP_083351.1 syntaxin-11

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell mediated cytotoxicity IMP
IMP: Inferred from mutant phenotype
23042080 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
acts upstream of or within cytotoxic T cell degranulation IMP
IMP: Inferred from mutant phenotype
23042080 MGI
acts upstream of or within natural killer cell degranulation IMP
IMP: Inferred from mutant phenotype
23042080 MGI
acts upstream of or within natural killer cell mediated cytotoxicity IMP
IMP: Inferred from mutant phenotype
23042080 MGI
acts upstream of or within neutrophil degranulation IMP
IMP: Inferred from mutant phenotype
23042080 MGI
Cellular Component GO Annotation Evidence References Source
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13975 STX11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stx11 NCBI NCBI:8676