WNT8A - Wnt family member 8A Gene

Also Known as WNT8D

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 7478

About WNT8A

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:138,077,367-138,092,365 (from NCBI)

This gene has 4 transcripts (splice variants), 275 orthologues and 18 paralogues. Low expression observed in reference dataset.

Summary

The Wnt gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the Wnt gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]

WNT8A Products (3)

mRNA Protein Name
NM_001300938.2 NP_001287867.1 protein Wnt-8a isoform 1 precursor
NM_001300939.2 NP_001287868.1 protein Wnt-8a isoform 2 precursor
NM_058244.4 NP_490645.1 protein Wnt-8a isoform 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables receptor ligand activity IDA
IDA: Inferred from direct assay
28733458 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in canonical Wnt signaling pathway IDA
IDA: Inferred from direct assay
28733458 GOA
involved in secondary palate development IMP
IMP: Inferred from mutant phenotype
18413325 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WNT8A Protein Structure

wnt

wnt: wnt family (36 - 336)

  • 0
  • 100
  • 200
  • 300
  • 351 a.a.
Protein Preferred Names Protein Names

protein Wnt-8a

  • WNT8d

関連疾患

Diseases Alias
Norrie Disease

  • Atrophia Bulborum Hereditaria

  • Episkopi Blindness

  • Pseudoglioma

  • ND

  • Norrie-Warburg Disease

  • Anderson-Warburg Syndrome

  • Fetal Iritis Syndrome

  • Norrie Syndrome

  • Norrie-Warburg Syndrome

  • Ndp

  • Congenital Progressive Oculo-Acoustico-Cerebral Degeneration

  • Norrie'S Disease

  • Oligophrenia Microphthalmus

  • Pseudoglioma Congenita

  • Whitnall-Norman Syndrome
Exudative Vitreoretinopathy

  • Familial Exudative Vitreoretinopathy

  • Fevr

  • Criswick-Schepens Syndrome

  • Exudative Vitreoretinopathy, Familial

  • Vitreoretinopathy, Exudative )

  • Exudative Vitreoretinopathy 1
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS15842 WNT8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus WNT8A RGD RGD:1306312
Macaca mulatta WNT8A VGNC VGNC:78801
Mus musculus WNT8A MGD MGI:107924
Felis catus WNT8A VGNC VGNC:67085
Bos taurus WNT8A VGNC VGNC:36964
Canis familiaris WNT8A VGNC VGNC:48429
Others WNT8A NCBI