WNT8A - Wnt family member 8A Gene

Homo sapiens

Also known as WNT8D

Gene ID: 7478 | Gene type: protein coding

About WNT8A

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:138,077,367-138,092,365 (from NCBI)

This gene has 4 transcripts (splice variants), 275 orthologues and 18 paralogues. Low expression observed in reference dataset.

Summary

The Wnt gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the Wnt gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]

WNT8A Products(3)

mRNA	Protein	Name
NM_001300938.2	NP_001287867.1	protein Wnt-8a isoform 1 precursor
NM_001300939.2	NP_001287868.1	protein Wnt-8a isoform 2 precursor
NM_058244.4	NP_490645.1	protein Wnt-8a isoform 3 precursor

WNT8A Protein Structure

wnt

0
100
200
300
351 a.a.

Protein Preferred Names

Protein Names

protein Wnt-8a

WNT8d

Related Diseases

Diseases

Alias

Norrie Disease

Atrophia Bulborum Hereditaria	Episkopi Blindness
Pseudoglioma	ND
Norrie-Warburg Disease	Anderson-Warburg Syndrome
Fetal Iritis Syndrome	Norrie Syndrome
Norrie-Warburg Syndrome	Ndp
Congenital Progressive Oculo-Acoustico-Cerebral Degeneration	Norrie'S Disease
Oligophrenia Microphthalmus	Pseudoglioma Congenita
Whitnall-Norman Syndrome

Exudative Vitreoretinopathy

Familial Exudative Vitreoretinopathy	Fevr
Criswick-Schepens Syndrome	Exudative Vitreoretinopathy, Familial
Vitreoretinopathy, Exudative )	Exudative Vitreoretinopathy 1

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15842	WNT8A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	WNT8A	RGD	RGD:1306312
Macaca mulatta	WNT8A	VGNC	VGNC:78801
Mus musculus	WNT8A	MGD	MGI:107924
Felis catus	WNT8A	VGNC	VGNC:67085
Bos taurus	WNT8A	VGNC	VGNC:36964
Canis familiaris	WNT8A	VGNC	VGNC:48429

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