Nhej1 - non-homologous end joining factor 1 Gene

Also Known as XLF; cernunnos; 1700029B21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75570

Summary

Predicted to enable DNA end binding activity and DNA Polymerase binding activity. Involved in double-strand break repair via nonhomologous end joining. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of DNA Ligase IV complex and nonhomologous end joining complex. Predicted to be active in site of double-strand break. Orthologous to human NHEJ1 (non-homologous end joining factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Nhej1 Products (1)

mRNA Protein Name
NM_029342.4 NP_083618.3 non-homologous end-joining factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30017584 MGI
Biological Process GO Annotation Evidence References Source
involved in double-strand break repair via nonhomologous end joining IMP
IMP: Inferred from mutant phenotype
27798842 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

non-homologous end-joining factor 1

  • XRCC4-like factor

  • nonhomologous end-joining factor 1

  • protein cernunnos

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148078 PFM03 Inhibitor 99.86% Unkown
HY-RS09281 NHEJ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nhej1 NCBI NCBI:79840