Ndufaf2 - NADH:ubiquinone oxidoreductase complex assembly factor 2 Gene

Also Known as mimitin; Ndufa12l; 1810058I14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75597

Summary

Acts upstream of or within mitochondrial respiratory chain complex I assembly and negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 10. Orthologous to human NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ndufaf2 Products (2)

mRNA Protein Name
NM_001127346.2 NP_001120818.1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 isoform 1
NM_001360140.2 NP_001347069.1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within mitochondrial respiratory chain complex I assembly IMP
IMP: Inferred from mutant phenotype
23702311 MGI
acts upstream of or within negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
22587331 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

  • MMTN

  • Myc-induced mitochondria protein

  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2

  • NDUFA12-like protein

  • mimitin, mitochondrial

  • myc-induced mitochondrial protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09138 NDUFAF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndufaf2 NCBI NCBI:91942