Rian - RNA imprinted and accumulated in nucleus Gene

Also Known as Meg8; 5530401N18Rik; C130089L09Rik

Species: Mus musculus

Gene Type: ncRNA
Gene ID: 75745

Summary

Acts upstream of or within several processes, including epithelial to mesenchymal transition; negative regulation of Notch signaling pathway; and negative regulation of hepatic stellate cell activation. Located in nucleus. Is expressed in several structures, including adrenal gland; central nervous system; gut; metanephros; and sensory organ. Orthologous to human MEG8 (maternally expressed 8, small nucleolar RNA host gene). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
22733778 MGI
involved in chromatin organization IDA
IDA: Inferred from direct assay
26005002 MGI
acts upstream of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
22733778 MGI
acts upstream of or within epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
29636669 MGI
acts upstream of or within negative regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
29636669 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
22733778 MGI
acts upstream of or within negative regulation of hepatic stellate cell activation IMP
IMP: Inferred from mutant phenotype
29636669 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11481034 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern