Klf17 - Kruppel-like factor 17 Gene

Also Known as Gzf; Zfp393; D4Ertd561e; 7420700M05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75753

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within gamete generation. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; and lower urinary tract. Orthologous to human KLF17 (Kruppel like factor 17). [provided by Alliance of Genome Resources, Apr 2022]

Klf17 Products (1)

mRNA Protein Name
NM_029416.2 NP_083692.2 Krueppel-like factor 17

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
19801974 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
19801974 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
19801974 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
19801974 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within gamete generation IDA
IDA: Inferred from direct assay
12351194 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19801974 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19801974 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 17

  • germ cell specific zinc finger protein

  • zinc finger protein 393

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07338 KLF17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf17 NCBI NCBI:128209