Slx1b - SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) Gene

Also Known as Giyd1; Giyd2; 1110030E23Rik; 2410170E21Rik; 4833422P03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75764

Summary

Predicted to enable 5'-flap Endonuclease activity and crossover junction endodeoxyribonuclease activity. Involved in positive regulation of t-circle formation and t-circle formation. Predicted to be located in nucleoplasm. Predicted to be part of Slx1-Slx4 complex. Used to study Fanconi-like syndrome. Orthologous to several human genes including SLX1A (SLX1 homolog A, structure-specific Endonuclease subunit). [provided by Alliance of Genome Resources, Apr 2022]

Slx1b Products (1)

mRNA Protein Name
NM_029420.4 NP_083696.2 structure-specific endonuclease subunit SLX1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of t-circle formation IMP
IMP: Inferred from mutant phenotype
22579284 MGI
involved in t-circle formation IMP
IMP: Inferred from mutant phenotype
22579284 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

structure-specific endonuclease subunit SLX1

  • GIY-YIG domain containing 2

  • GIY-YIG domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13388 SLX1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slx1b NCBI NCBI:79008