MPPED1 - metallophosphoesterase domain containing 1 Gene

Also Known as 239AB; FAM1A; C22orf1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 758

About MPPED1

Cytogenetic location: 22q13.2 Genomic coordinates (GRCh38): 22:43,412,014-43,507,848 (from NCBI)

This gene has 6 transcripts (splice variants), 205 orthologues and 1 paralogue. Biased expression in brain (RPKM 6.2) and liver (RPKM 1.2).

Summary

Predicted to enable hydrolase activity. [provided by Alliance of Genome Resources, Apr 2022]

MPPED1 Products (2)

mRNA Protein Name
NM_001044370.2 NP_001037835.1 metallophosphoesterase domain-containing protein 1
NM_001362786.2 NP_001349715.1 metallophosphoesterase domain-containing protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MPPED1 Protein Structure

Metallophos

Metallophos: Calcineurin-like phosphoesterase (106 - 287)

  • 0
  • 100
  • 200
  • 300
  • 326 a.a.
Protein Preferred Names Protein Names

metallophosphoesterase domain-containing protein 1

  • adult brain protein 239

Related Diseases

Diseases Alias
Mitochondrial Complex I Deficiency, Nuclear Type 33

  • MC1DN33

  • Nuclear Type Mitochondrial Complex I Deficiency 33

  • Mitochondrial Complex 1 Deficiency, Nuclear Type 33
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08627 MPPED1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MPPED1 VGNC VGNC:95362
Canis familiaris MPPED1 VGNC VGNC:43349
Rattus norvegicus MPPED1 RGD RGD:1308244
Bos taurus MPPED1 VGNC VGNC:106826
Mus musculus MPPED1 MGD MGI:106316
Others MPPED1 NCBI