Crppa - CDP-L-ribitol pyrophosphorylase A Gene

Also Known as Ispd; 4930579E17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75847

Summary

Predicted to enable D-ribitol-5-phosphate cytidylyltransferase activity and protein homodimerization activity. Acts upstream of or within axon guidance and protein glycosylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in brain. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2U and congenital muscular dystrophy-dystroglycanopathy A7. Orthologous to human CRPPA (CDP-L-ribitol pyrophosphorylase A). [provided by Alliance of Genome Resources, Apr 2022]

Crppa Products (5)

mRNA Protein Name
NM_001289502.1 NP_001276431.1 D-ribitol-5-phosphate cytidylyltransferase isoform 2
NM_001289503.1 NP_001276432.1 D-ribitol-5-phosphate cytidylyltransferase isoform 3
NM_001289504.1 NP_001276433.1 D-ribitol-5-phosphate cytidylyltransferase isoform 4
NM_001364305.1 NP_001351234.1 D-ribitol-5-phosphate cytidylyltransferase isoform 5
NM_178629.6 NP_848744.2 D-ribitol-5-phosphate cytidylyltransferase isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
23217742 MGI
acts upstream of or within protein glycosylation IMP
IMP: Inferred from mutant phenotype
23217742 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

D-ribitol-5-phosphate cytidylyltransferase

  • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein

  • isoprenoid synthase domain containing

  • isoprenoid synthase domain-containing protein

  • notch1-induced protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03196 CRPPA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crppa NCBI NCBI:729920