Adhfe1 - alcohol dehydrogenase, iron containing, 1 Gene

Also Known as HOT; Adh8; 6330565B14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76187

Summary

Predicted to enable alcohol dehydrogenase (NAD+) activity and hydroxyacid-oxoacid transhydrogenase activity. Predicted to be involved in glutamate catabolic process via 2-oxoglutarate. Located in mitochondrion. Is expressed in several structures, including brain; cranium; genitourinary system; sensory organ; and spinal cord. Orthologous to human ADHFE1 (alcohol dehydrogenase iron containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Adhfe1 Products (4)

mRNA Protein Name
NM_001357376.1 NP_001344305.1 hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform 2
NM_001357377.1 NP_001344306.1 hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform 2
NM_001357378.1 NP_001344307.1 hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform 3
NM_175236.5 NP_780445.1 hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
17559793 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hydroxyacid-oxoacid transhydrogenase, mitochondrial

  • Fe-containing alcohol dehydrogenase 1

  • alcohol dehydrogenase 8

  • alcohol dehydrogenase iron-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00375 ADHFE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adhfe1 NCBI NCBI:137872