Trp53rkb - transformation related protein 53 regulating kinase B Gene

Also known as PRPK; Nori-2; Tp53rk; Tp53rkb; Trp53rk; Trp53tk; mNori-2p; 2810408M09Rik; 4933401B08Rik; 5630401H01Rik

About Trp53rkb

Summary

Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to be located in cytoplasm. Predicted to be part of EKC/KEOPS complex. Predicted to be active in nucleus. Is expressed in central nervous system; forelimb bud; genitourinary system; liver; and retina. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase). [provided by Alliance of Genome Resources, Apr 2022]