Rflnb - refilin B Gene

Also Known as cfm; Fam101b; RefilinB; 1500005K14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76566

Summary

Predicted to enable filamin binding activity. Acts upstream of or within several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Located in actin filament bundle. Is expressed in several structures, including 1st branchial arch; embryo ectoderm; genital tubercle; lung; and occipital myotome. Orthologous to human RFLNB (refilin B). [provided by Alliance of Genome Resources, Apr 2022]

Rflnb Products (1)

mRNA Protein Name
NM_029658.1 NP_083934.1 refilin-B

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IGI
IGI: Inferred from genetic interaction
21709252 MGI
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21709252 MGI
acts upstream of or within actin filament bundle organization IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within epithelial to mesenchymal transition IGI
IGI: Inferred from genetic interaction
21709252 MGI
acts upstream of or within negative regulation of bone mineralization involved in bone maturation IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within negative regulation of chondrocyte development IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
24436304 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
21709252 MGI
located in actin filament bundle IDA
IDA: Inferred from direct assay
24436304 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

refilin-B

  • family with sequence similarity 101, member B

  • filamin-interacting protein FAM101B

  • protein FAM101B

  • regulator of filamin protein B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11874 RFLNB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rflnb NCBI NCBI:359845