Snx27 - sorting nexin family member 27 Gene

Also Known as ESTM45; ESTM47; 5730552M22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76742

Summary

Predicted to enable ionotropic glutamate receptor binding activity and phosphatidylinositol-3-phosphate binding activity. Acts upstream of or within endosomal transport. Located in endosome. Is expressed in several structures, including adipose tissue; eye; gut; nervous system; and reproductive system. Orthologous to human SNX27 (sorting nexin 27). [provided by Alliance of Genome Resources, Apr 2022]

Snx27 Products (2)

mRNA Protein Name
NM_001082484.2 NP_001075953.1 sorting nexin-27 isoform 1
NM_029721.2 NP_083997.1 sorting nexin-27 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21300787 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endosomal transport IMP
IMP: Inferred from mutant phenotype
21300787 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
21300787 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IEP
IEP: Inferred from expression pattern
23524343 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
21300787 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
23524343 MGI
is active in Schaffer collateral - CA1 synapse IEP
IEP: Inferred from expression pattern
23524343 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
23524343 MGI
located in endosome IDA
IDA: Inferred from direct assay
23382219 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23524343 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
23524343 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23524343 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
24458027 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
24458027 MGI
is active in postsynaptic early endosome IDA
IDA: Inferred from direct assay
24458027 MGI
is active in postsynaptic recycling endosome IDA
IDA: Inferred from direct assay
24458027 MGI
is active in postsynaptic recycling endosome IMP
IMP: Inferred from mutant phenotype
24458027 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorting nexin-27

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13537 SNX27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snx27 NCBI NCBI:81609