Snx27 - sorting nexin family member 27 Gene

Mus musculus

Also known as ESTM45; ESTM47; 5730552M22Rik

Gene ID: 76742 | Gene type: protein coding

About Snx27

Summary

Predicted to enable ionotropic glutamate receptor binding activity and phosphatidylinositol-3-phosphate binding activity. Acts upstream of or within endosomal transport. Located in endosome. Is expressed in several structures, including adipose tissue; eye; gut; nervous system; and reproductive system. Orthologous to human SNX27 (sorting nexin 27). [provided by Alliance of Genome Resources, Apr 2022]

Snx27 Products(2)

mRNA	Protein	Name
NM_001082484.2	NP_001075953.1	sorting nexin-27 isoform 1
NM_029721.2	NP_083997.1	sorting nexin-27 isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21300787	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within endosomal transport	IMP IMP: Inferred from mutant phenotype	21300787	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IDA IDA: Inferred from direct assay	21300787	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IEP IEP: Inferred from expression pattern	23524343	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IMP IMP: Inferred from mutant phenotype	21300787	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in Schaffer collateral - CA1 synapse	IDA IDA: Inferred from direct assay	23524343	MGI
is active in Schaffer collateral - CA1 synapse	IEP IEP: Inferred from expression pattern	23524343	MGI
is active in Schaffer collateral - CA1 synapse	IMP IMP: Inferred from mutant phenotype	23524343	MGI
located in endosome	IDA IDA: Inferred from direct assay	23382219	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	23524343	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	23524343	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	23524343	MGI
is active in postsynapse	IDA IDA: Inferred from direct assay	24458027	MGI
is active in postsynapse	IMP IMP: Inferred from mutant phenotype	24458027	MGI
is active in postsynaptic early endosome	IDA IDA: Inferred from direct assay	24458027	MGI
is active in postsynaptic recycling endosome	IDA IDA: Inferred from direct assay	24458027	MGI
is active in postsynaptic recycling endosome	IMP IMP: Inferred from mutant phenotype	24458027	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sorting nexin-27

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13537	SNX27 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Snx27	NCBI	NCBI:81609

Name
Email *

	Sorry, but the email address you supplied was invalid.