2. Gene
  3. Ppfia3 - protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 Gene

Ppfia3 - protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2410127E16Rik

Gene ID: 76787 | Gene type: protein coding

About Ppfia3

Summary

Involved in synaptic vesicle docking. Located in acrosomal vesicle; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Is expressed in nervous system; nose; and retina layer. Orthologous to human PPFIA3 (PTPRF interacting protein alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Ppfia3 Products(1)

mRNA Protein Name
NM_029741.2 NP_084017.2 liprin-alpha-3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in synaptic vesicle docking IDA
IDA: Inferred from direct assay
29439199 MGI
involved in synaptic vesicle docking IMP
IMP: Inferred from mutant phenotype
29439199 MGI
involved in synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
29439199 MGI
involved in synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
29439199 MGI
Cellular Component GO Annotation Evidence Reference Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
23124857 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29439199 MGI
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
29439199 MGI
is active in presynaptic active zone cytoplasmic component IDA
IDA: Inferred from direct assay
29439199 MGI
is active in synapse IDA
IDA: Inferred from direct assay
21618221 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liprin-alpha-3

Liprin-alpha3

PTPRF-interacting protein alpha-3

protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10941 PPFIA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppfia3 NCBI NCBI:8541