Sdccag8 - serologically defined colon cancer antigen 8 Gene

Also Known as Cccap; 2700048G21Rik; 5730470G24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76816

Summary

Involved in establishment of cell polarity; regulation of cilium assembly; and tube formation. Acts upstream of or within microtubule organizing center organization and neuron migration. Located in cytoplasm; microtubule organizing center; and photoreceptor cell cilium. Is expressed in brain. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 16 and Senior-Loken syndrome. Orthologous to human SDCCAG8 (SHH signaling and ciliogenesis regulator SDCCAG8). [provided by Alliance of Genome Resources, Apr 2022]

Sdccag8 Products (2)

mRNA Protein Name
NM_001357390.1 NP_001344319.1 serologically defined colon cancer antigen 8 homolog isoform 2
NM_029756.3 NP_084032.1 serologically defined colon cancer antigen 8 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25088364 MGI
Biological Process GO Annotation Evidence References Source
involved in establishment of cell polarity IMP
IMP: Inferred from mutant phenotype
20835237 MGI
acts upstream of or within microtubule organizing center organization IMP
IMP: Inferred from mutant phenotype
25088364 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
25088364 MGI
involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
27224062 MGI
involved in tube formation IMP
IMP: Inferred from mutant phenotype
20835237 MGI
Cellular Component GO Annotation Evidence References Source
located in centriolar satellite IDA
IDA: Inferred from direct assay
25088364 MGI
located in centriole IDA
IDA: Inferred from direct assay
25088364 MGI
located in centrosome IDA
IDA: Inferred from direct assay
12559564 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
29899041 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
25088364 MGI
located in photoreceptor cell cilium IDA
IDA: Inferred from direct assay
29899041 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serologically defined colon cancer antigen 8 homolog

  • centrosomal colon cancer autoantigen protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12585 SDCCAG8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdccag8 NCBI NCBI:10806