2. Gene
  3. Sdccag8 - serologically defined colon cancer antigen 8 Gene

Sdccag8 - serologically defined colon cancer antigen 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cccap; 2700048G21Rik; 5730470G24Rik

Gene ID: 76816 | Gene type: protein coding

About Sdccag8

Summary

Involved in establishment of cell polarity; regulation of cilium assembly; and tube formation. Acts upstream of or within microtubule organizing center organization and neuron migration. Located in cytoplasm; microtubule organizing center; and photoreceptor cell cilium. Is expressed in brain. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 16 and Senior-Loken syndrome. Orthologous to human SDCCAG8 (SHH signaling and ciliogenesis regulator SDCCAG8). [provided by Alliance of Genome Resources, Apr 2022]

Sdccag8 Products(2)

mRNA Protein Name
NM_001357390.1 NP_001344319.1 serologically defined colon cancer antigen 8 homolog isoform 2
NM_029756.3 NP_084032.1 serologically defined colon cancer antigen 8 homolog isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25088364 MGI
Biological Process GO Annotation Evidence Reference Source
involved in establishment of cell polarity IMP
IMP: Inferred from mutant phenotype
20835237 MGI
acts upstream of or within microtubule organizing center organization IMP
IMP: Inferred from mutant phenotype
25088364 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
25088364 MGI
involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
27224062 MGI
involved in tube formation IMP
IMP: Inferred from mutant phenotype
20835237 MGI
Cellular Component GO Annotation Evidence Reference Source
located in centriolar satellite IDA
IDA: Inferred from direct assay
25088364 MGI
located in centriole IDA
IDA: Inferred from direct assay
25088364 MGI
located in centrosome IDA
IDA: Inferred from direct assay
12559564 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
29899041 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
25088364 MGI
located in photoreceptor cell cilium IDA
IDA: Inferred from direct assay
29899041 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serologically defined colon cancer antigen 8 homolog

centrosomal colon cancer autoantigen protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12585 SDCCAG8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdccag8 NCBI NCBI:10806