Ddrgk1 - DDRGK domain containing 1 Gene

Also Known as Ufbp1; 1110001I20Rik; 2600009E05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77006

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and ubiquitin-like protein Ligase binding activity. Involved in several processes, including cartilage development; negative regulation of IRE1-mediated unfolded protein response; and positive regulation of protein localization to endoplasmic reticulum. Located in endoplasmic reticulum. Is expressed in central nervous system; genitourinary system; heart; and liver. Orthologous to human DDRGK1 (DDRGK domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddrgk1 Products (1)

mRNA Protein Name
NM_029832.2 NP_084108.1 DDRGK domain-containing protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21494687 MGI
Biological Process GO Annotation Evidence References Source
involved in cartilage development IMP
IMP: Inferred from mutant phenotype
28263186 MGI
involved in negative regulation of IRE1-mediated unfolded protein response IMP
IMP: Inferred from mutant phenotype
28128204 MGI
involved in negative regulation of PERK-mediated unfolded protein response IMP
IMP: Inferred from mutant phenotype
30842412 MGI
involved in positive regulation of plasma cell differentiation IMP
IMP: Inferred from mutant phenotype
30842412 MGI
involved in positive regulation of protein localization to endoplasmic reticulum IDA
IDA: Inferred from direct assay
21494687 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
21494687 MGI
Cellular Component GO Annotation Evidence References Source
is active in endoplasmic reticulum IDA
IDA: Inferred from direct assay
37795761 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21494687 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DDRGK domain-containing protein 1

  • UFM1-binding and PCI domain-containing protein 1

  • UFM1-binding protein 1 containing a PCI domain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03626 DDRGK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddrgk1 NCBI NCBI:65992