2. Gene
  3. Arfgap2 - ADP-ribosylation factor GTPase activating protein 2 Gene

Arfgap2 - ADP-ribosylation factor GTPase activating protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Zfp289; 2310032E02Rik

Gene ID: 77038 | Gene type: protein coding

About Arfgap2

Summary

This gene encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. This gene product stimulates the hydrolysis of ARF1-bound GTP, which may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. It may regulate the retrograde transport from the Golgi complex to the endoplasmic reticulum. Expression of this gene has been shown to be controlled by inhibitor of DNA binding 1 (Id1). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 6. [provided by RefSeq, Oct 2009]

Arfgap2 Products(2)

mRNA Protein Name
NM_001166024.1 NP_001159496.1 ADP-ribosylation factor GTPase-activating protein 2 isoform 1
NM_023854.2 NP_076343.2 ADP-ribosylation factor GTPase-activating protein 2 isoform 2
Protein Preferred Names Protein Names

ADP-ribosylation factor GTPase-activating protein 2

ARF GAP 2

GTPase-activating protein ZNF289

zinc finger protein 289

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00900 ARFGAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arfgap2 NCBI NCBI:84364