Ston1 - stonin 1 Gene

Also Known as Salf; Sblf; 4921524J06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77057

Summary

Enables cargo adaptor activity. Acts upstream of or within several processes, including cell-substrate junction organization; platelet-derived growth factor receptor signaling pathway; and ruffle assembly. Located in cell leading edge; cell projection; and clathrin-coated pit. Is expressed in genitourinary system. Orthologous to several human genes including STON1-GTF2A1L (STON1-GTF2A1L readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Ston1 Products (1)

mRNA Protein Name
NM_029858.2 NP_084134.2 stonin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cargo adaptor activity IDA
IDA: Inferred from direct assay
26437238 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26437238 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
26437238 MGI
acts upstream of or within endocytosis IMP
IMP: Inferred from mutant phenotype
26437238 MGI
acts upstream of or within focal adhesion assembly IMP
IMP: Inferred from mutant phenotype
26437238 MGI
acts upstream of or within focal adhesion disassembly IMP
IMP: Inferred from mutant phenotype
26437238 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26437238 MGI
acts upstream of or within ruffle assembly IMP
IMP: Inferred from mutant phenotype
26437238 MGI
acts upstream of or within substrate-dependent cell migration IGI
IGI: Inferred from genetic interaction
26437238 MGI
acts upstream of or within substrate-dependent cell migration IMP
IMP: Inferred from mutant phenotype
26437238 MGI
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
26437238 MGI
located in cell projection IDA
IDA: Inferred from direct assay
26437238 MGI
located in clathrin-coated pit IDA
IDA: Inferred from direct assay
26437238 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

stonin-1

  • stoned B-like factor

  • stoned B/TFIIA-alpha/beta-like factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13952 STON1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ston1 NCBI NCBI:11037