Heg1 - heart development protein with EGF-like domains 1 Gene

Also Known as Gm629; 4632417D23Rik; 5530401I02Rik; 9530025L16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77446

Summary

Predicted to enable calcium ion binding activity. Acts upstream of or within several processes, including circulatory system development; endothelial cell morphogenesis; and lymph circulation. Located in cell-cell junction and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human HEG1 (heart development protein with EGF like domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Heg1 Products (1)

mRNA Protein Name
NM_175256.5 NP_780465.4 protein HEG homolog 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19151727 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac atrium morphogenesis IGI
IGI: Inferred from genetic interaction
22898778 MGI
acts upstream of or within cardiac atrium morphogenesis IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within cardiac muscle tissue growth IGI
IGI: Inferred from genetic interaction
22898778 MGI
acts upstream of or within cell-cell junction organization IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within endothelial cell development IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within endothelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of fibroblast growth factor production IGI
IGI: Inferred from genetic interaction
22898778 MGI
acts upstream of or within heart development IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within in utero embryonic development IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within lymph circulation IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within lymph vessel development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within multicellular organism growth IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within pericardium development IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within pericardium development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within positive regulation of fibroblast growth factor production IGI
IGI: Inferred from genetic interaction
22898778 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within regulation of body fluid levels IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within vasculature development IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within vasculogenesis IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within venous blood vessel morphogenesis IGI
IGI: Inferred from genetic interaction
19151727 MGI
acts upstream of or within ventricular septum development IMP
IMP: Inferred from mutant phenotype
19151727 MGI
acts upstream of or within ventricular trabecula myocardium morphogenesis IGI
IGI: Inferred from genetic interaction
22898778 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19151727 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
19151727 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19151727 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein HEG homolog 1

  • HEG homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06113 HEG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Heg1 NCBI NCBI:57493