Cpt1c - carnitine palmitoyltransferase 1c Gene

Also Known as CPT IC; CPT1-B; CPTI-B; CPT I-C; 6530437J22Rik; 9630004I06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78070

Summary

Predicted to enable carnitine O-palmitoyltransferase activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Located in several cellular components, including dendrite; endoplasmic reticulum; and postsynapse. Is integral component of endoplasmic reticulum membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 73. Orthologous to human CPT1C (carnitine palmitoyltransferase 1C). [provided by Alliance of Genome Resources, Apr 2022]

Cpt1c Products (3)

mRNA Protein Name
NM_001252470.1 NP_001239399.1 carnitine O-palmitoyltransferase 1, brain isoform isoform 1
NM_001357670.1 NP_001344599.1 carnitine O-palmitoyltransferase 1, brain isoform isoform 2
NM_153679.2 NP_710146.1 carnitine O-palmitoyltransferase 1, brain isoform isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyl-(protein) hydrolase activity IDA
IDA: Inferred from direct assay
30135643 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
26338711 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IEP
IEP: Inferred from expression pattern
26338711 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
26338711 MGI
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
located in axon IDA
IDA: Inferred from direct assay
25751282 MGI
located in dendrite IDA
IDA: Inferred from direct assay
25751282 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
25751282 MGI
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
22539351 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
18192268 MGI
is active in endoplasmic reticulum membrane IEP
IEP: Inferred from expression pattern
22539351 MGI
is active in endoplasmic reticulum membrane IMP
IMP: Inferred from mutant phenotype
22539351 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22539351 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
22539351 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22539351 MGI
NOT located in mitochondrion IDA
IDA: Inferred from direct assay
18192268 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
22539351 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
22539351 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
22539351 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carnitine O-palmitoyltransferase 1, brain isoform

  • carnitine palmitoyltransferase 1, brain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03124 CPT1C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpt1c NCBI NCBI:126129