Scyl1 - SCY1-like 1 (S. cerevisiae) Gene

Also Known as mdf; mfd; Ntkl; p105; 2810011O19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78891

Summary

Predicted to enable ATP binding activity and protein kinase activity. Acts upstream of or within cellular protein localization; inflammatory response; and neuron differentiation. Located in cytoplasm. Part of COPI vesicle coat. Is expressed in hindbrain; jaw; otic capsule; and skeleton. Used to study hereditary ataxia. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 21. Orthologous to human SCYL1 (SCY1 like pseudokinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Scyl1 Products (3)

mRNA Protein Name
NM_001361921.1 NP_001348850.1 N-terminal kinase-like protein isoform 2
NM_001361922.1 NP_001348851.1 N-terminal kinase-like protein isoform 3
NM_023912.3 NP_076401.1 N-terminal kinase-like protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12783284 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inflammatory response IGI
IGI: Inferred from genetic interaction
29437892 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
29437892 MGI
acts upstream of or within neuron development IGI
IGI: Inferred from genetic interaction
29437892 MGI
acts upstream of or within protein localization IGI
IGI: Inferred from genetic interaction
29437892 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
29437892 MGI
acts upstream of or within spinal cord motor neuron differentiation IGI
IGI: Inferred from genetic interaction
29437892 MGI
acts upstream of or within spinal cord motor neuron differentiation IMP
IMP: Inferred from mutant phenotype
29437892 MGI
Cellular Component GO Annotation Evidence References Source
part of COPI vesicle coat IDA
IDA: Inferred from direct assay
18556652 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12783284 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-terminal kinase-like protein

  • 105 kDa kinase-like protein

  • SCY1-like protein 1

  • mitosis-associated kinase-like protein NTKL

  • ubiquitous protein kinase-like (105 kDa)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02082 CCL13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12575 SCYL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scyl1 NCBI NCBI:57410