2. Gene
  3. Pigt - phosphatidylinositol glycan anchor biosynthesis, class T Gene

Pigt - phosphatidylinositol glycan anchor biosynthesis, class T Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NDAP; Ndap7; CGI-06; 2510012P17Rik; 4930534E15Rik

Gene ID: 78928 | Gene type: protein coding

About Pigt

Summary

Involved in attachment of GPI anchor to protein. Acts upstream of or within neuron apoptotic process and neuron differentiation. Located in cytoplasmic vesicle. Part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 3 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGT (phosphatidylinositol glycan anchor biosynthesis class T). [provided by Alliance of Genome Resources, Apr 2022]

Pigt Products(5)

mRNA Protein Name
NM_001362644.2 NP_001349573.1 GPI transamidase component PIG-T isoform 2 precursor
NM_001362645.2 NP_001349574.1 GPI transamidase component PIG-T isoform 3
NM_001378795.1 NP_001365724.1 GPI transamidase component PIG-T isoform 4
NM_001407281.1 NP_001394210.1 GPI transamidase component PIG-T isoform 1 precursor
NM_133779.3 NP_598540.2 GPI transamidase component PIG-T isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in attachment of GPI anchor to protein IMP
IMP: Inferred from mutant phenotype
11483512 MGI
acts upstream of or within neuron apoptotic process IDA
IDA: Inferred from direct assay
16516892 MGI
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
16516892 MGI
Cellular Component GO Annotation Evidence Reference Source
part of GPI-anchor transamidase complex IDA
IDA: Inferred from direct assay
11483512 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
16516892 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
16516892 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GPI transamidase component PIG-T

neuronal development-associated protein 7

phosphatidylinositol-glycan biosynthesis class T protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10502 PIGT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pigt NCBI NCBI:51604