2. Gene
  3. Arhgef11 - Rho guanine nucleotide exchange factor 11 Gene

Arhgef11 - Rho guanine nucleotide exchange factor 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gtrap48

Gene ID: 78966 | Gene type: protein coding

About Arhgef11

Summary

Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in Rho protein signal transduction and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Orthologous to human ARHGEF11 (Rho guanine nucleotide exchange factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef11 Products(1)

mRNA Protein Name
NM_023982.2 NP_076472.2 rho guanine nucleotide exchange factor 11
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
11242047 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11242047 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of L-glutamate import across plasma membrane IMP
IMP: Inferred from mutant phenotype
11242047 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 11

Rho guanine nucleotide exchange factor (GEF) 11

RhoGEF glutamate transport modulator GTRAP48

glutamate transporter EAAT4 associated protein 48

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00948 ARHGEF11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgef11 NCBI NCBI:9826