Arhgef11 - Rho guanine nucleotide exchange factor 11 Gene

Also Known as Gtrap48

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 78966

Summary

Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in Rho protein signal transduction and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Orthologous to human ARHGEF11 (Rho guanine nucleotide exchange factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Arhgef11 Products (1)

mRNA Protein Name
NM_023982.2 NP_076472.2 rho guanine nucleotide exchange factor 11

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
11242047 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11242047 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of L-glutamate import across plasma membrane IMP
IMP: Inferred from mutant phenotype
11242047 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 11

  • Rho guanine nucleotide exchange factor (GEF) 11

  • RhoGEF glutamate transport modulator GTRAP48

  • glutamate transporter EAAT4 associated protein 48

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00948 ARHGEF11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgef11 NCBI NCBI:9826