2. Gene
  3. Mhrt - myosin heavy chain associated RNA transcript Gene

Mhrt - myosin heavy chain associated RNA transcript Gene

  • Gene
  • Ortholog
Mus musculus

Also known as Myheart; D830015G02Rik

Gene ID: 791403 | Gene type: ncRNA

About Mhrt

Summary

This gene encodes a spliced long non-coding RNA that may act as a cardioprotective agent in the heart. This transcript is thought to regulate chromatin remodeling by acting as a decoy to the Brg1 chromatin repressor complex thus preventing it from binding to its genomic targets. Blocking the actions of Brg1 may be crucial in protecting the heart from pathological hypertrophy. [provided by RefSeq, Dec 2014]

Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25119045 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within chromatin remodeling IDA
IDA: Inferred from direct assay
25119045 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Orthologs Information

Species Symbol Source ID
Homo sapiens Mhrt NCBI NCBI:104564225