Mhrt - myosin heavy chain associated RNA transcript Gene
Also Known as Myheart; D830015G02Rik
Species: Mus musculus
Summary
This gene encodes a spliced long non-coding RNA that may act as a cardioprotective agent in the heart. This transcript is thought to regulate chromatin remodeling by acting as a decoy to the Brg1 chromatin repressor complex thus preventing it from binding to its genomic targets. Blocking the actions of Brg1 may be crucial in protecting the heart from pathological hypertrophy. [provided by RefSeq, Dec 2014]
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25119045 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within chromatin remodeling |
IDA
IDA: Inferred from direct assay
|
25119045 | MGI |