Slc6a11 - solute carrier family 6 member 11 Gene

Also Known as Gat3; Gabt4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79213

Summary

Enables gamma-aminobutyric acid:sodium symporter activity and neurotransmitter binding activity. Involved in brain development; neurotransmitter reuptake; and response to xenobiotic stimulus. Located in cell projection; cytoplasm; and membrane. Is active in GABA-ergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Biomarker of visual epilepsy. Orthologous to human SLC6A11 (solute carrier family 6 member 11). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a11 Products (1)

mRNA Protein Name
NM_024372.2 NP_077348.1 sodium- and chloride-dependent GABA transporter 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amino acid binding IDA
IDA: Inferred from direct assay
1400419 RGD
enables gamma-aminobutyric acid:sodium:chloride symporter activity IDA
IDA: Inferred from direct assay
1400419 RGD
Biological Process GO Annotation Evidence References Source
involved in neurotransmitter transport IDA
IDA: Inferred from direct assay
1400419 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17408599 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
24368619 RGD
located in cell projection IDA
IDA: Inferred from direct assay
12898208 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
8731228 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
24368619 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
24368619 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium- and chloride-dependent GABA transporter 3

  • GABA transporter GAT-3

  • GAT-3

  • solute carrier family 6 (neurotransmitter transporter), member 11

  • solute carrier family 6 (neurotransmitter transporter, GABA), member 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13297 SLC6A11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc6a11 NCBI NCBI:6538