Gja3 - gap junction protein, alpha 3 Gene

Also Known as Cxnj1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79217

Summary

Enables gap junction hemi-channel activity and identical protein binding activity. Involved in response to hydrogen peroxide and response to pH. Located in gap junction and membrane raft. Used to study cataract. Human ortholog(s) of this gene implicated in cataract 14 multiple types. Orthologous to human GJA3 (Gap Junction Protein alpha 3). [provided by Alliance of Genome Resources, Apr 2022]

Gja3 Products (1)

mRNA Protein Name
NM_024376.3 NP_077352.2 gap junction alpha-3 protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gap junction channel activity IDA
IDA: Inferred from direct assay
1659572 RGD
enables gap junction hemi-channel activity IDA
IDA: Inferred from direct assay
17715132 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
9151687 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15467523 RGD
Biological Process GO Annotation Evidence References Source
involved in response to hydrogen peroxide IDA
IDA: Inferred from direct assay
15467523 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
11889584 RGD
Cellular Component GO Annotation Evidence References Source
located in gap junction IDA
IDA: Inferred from direct assay
1659572 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction alpha-3 protein

  • connexin j1

  • connexin-46

  • cx46

  • gap junction membrane channel protein alpha 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05442 GJA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gja3 NCBI NCBI:2700