Abca2 - ATP binding cassette subfamily A member 2 Gene

Also Known as Abc2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79248

Summary

Enables ATP binding activity. Involved in central nervous system myelin formation; negative regulation of lipid biosynthetic process; and positive regulation of amyloid-beta formation. Located in cytoplasmic vesicle; lysosomal membrane; and microtubule organizing center. Orthologous to human ABCA2 (ATP binding cassette subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Abca2 Products (1)

mRNA Protein Name
NM_024396.1 NP_077372.1 ATP-binding cassette sub-family A member 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
10970803 RGD
Biological Process GO Annotation Evidence References Source
involved in central nervous system myelin formation IDA
IDA: Inferred from direct assay
12210128 RGD
acts upstream of negative regulation of low-density lipoprotein receptor activity IDA
IDA: Inferred from direct assay
21810484 RGD
acts upstream of negative regulation of steroid metabolic process IMP
IMP: Inferred from mutant phenotype
24201375 RGD
involved in positive regulation of amyloid-beta formation IMP
IMP: Inferred from mutant phenotype
22086926 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
16539677 RGD
located in lysosomal membrane IDA
IDA: Inferred from direct assay
11157071 RGD
located in microtubule organizing center IDA
IDA: Inferred from direct assay
16539677 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family A member 2

  • ATP-binding cassette 2

  • ATP-binding cassette transporter 2

  • ATP-binding cassette, sub-family A (ABC1), member 2

  • ATP-binding cassette, subfamily A (ABC1), member 2