Hnrnpd - heterogeneous nuclear ribonucleoprotein D Gene

Also Known as Auf1; Hnrpd

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79256

Summary

Enables chromatin binding activity; histone deacetylase binding activity; and nucleic acid binding activity. Involved in several processes, including cellular response to estradiol stimulus; cellular response to organonitrogen compound; and regulation of mRNA stability. Located in cytosol and nucleus. Used to study uremia. Biomarker of hepatocellular carcinoma. Orthologous to human HNRNPD (heterogeneous nuclear ribonucleoprotein D). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpd Products (4)

mRNA Protein Name
NM_001082539.1 NP_001076008.1 heterogeneous nuclear ribonucleoprotein D0 isoform b
NM_001082540.1 NP_001076009.1 heterogeneous nuclear ribonucleoprotein D0 isoform c
NM_001082541.1 NP_001076010.1 heterogeneous nuclear ribonucleoprotein D0 isoform d
NM_024404.2 NP_077380.2 heterogeneous nuclear ribonucleoprotein D0 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
18413351 RGD
enables histone deacetylase binding IPI
IPI: Inferred from physical interaction
18413351 RGD
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
16113063 RGD
enables mRNA binding IDA
IDA: Inferred from direct assay
18583400 RGD
enables minor groove of adenine-thymine-rich DNA binding IDA
IDA: Inferred from direct assay
18413351 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16518874 RGD
Biological Process GO Annotation Evidence References Source
involved in 3'-UTR-mediated mRNA destabilization IMP
IMP: Inferred from mutant phenotype
20805360 RGD
involved in cellular response to amino acid stimulus IEP
IEP: Inferred from expression pattern
16569663 RGD
involved in cellular response to estradiol stimulus IEP
IEP: Inferred from expression pattern
22216273 RGD
involved in cellular response to nitric oxide IDA
IDA: Inferred from direct assay
16683234 RGD
involved in cellular response to putrescine IDA
IDA: Inferred from direct assay
20805360 RGD
involved in cerebellum development IEP
IEP: Inferred from expression pattern
19115409 RGD
involved in hepatocyte dedifferentiation IEP
IEP: Inferred from expression pattern
20102719 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
20102719 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
16683234 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20102719 RGD
involved in response to calcium ion IDA
IDA: Inferred from direct assay
18583400 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
20375275 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
11742537 RGD
involved in response to rapamycin IDA
IDA: Inferred from direct assay
17603996 RGD
involved in response to sodium phosphate IDA
IDA: Inferred from direct assay
18583400 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
22238095 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22238095 RGD
is active in postsynaptic density EXP
EXP: Inferred from Experiment
22238095 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
22238095 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein D0

  • AU-rich element RNA-binding factor 1

  • AU-rich element RNA-binding protein 1

  • RNA binding protein p45AUF1

  • hnRNP D0

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06267 HNRNPD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21865 Hnrnpd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnrnpd NCBI NCBI:3184