Clcnka - chloride voltage-gated channel Ka Gene

Rattus norvegicus

Also known as Clcnk1

Gene ID: 79425 | Gene type: protein coding

About Clcnka

Summary

This gene is a member of the CLC family of voltage-gated chloride channels. The gene is located adjacent to a highly similar Chloride Channel gene on chromosome 5. This gene is syntenic with human CLCNKB (geneID:1188).[provided by RefSeq, Sep 2009]

Clcnka Products(1)

mRNA	Protein	Name
NM_053327.2	NP_445779.2	chloride channel protein ClC-Ka

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chloride channel activity	IDA IDA: Inferred from direct assay	7680033	RGD
enables voltage-gated monoatomic ion channel activity	IDA IDA: Inferred from direct assay	16849430	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in body fluid secretion	IEP IEP: Inferred from expression pattern	7680033	RGD
involved in kidney development	IEP IEP: Inferred from expression pattern	11479722	RGD
involved in response to calcium ion	IEP IEP: Inferred from expression pattern	7814604	RGD
involved in response to pH	IEP IEP: Inferred from expression pattern	7814604	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	7814604	RGD
located in basolateral plasma membrane	IDA IDA: Inferred from direct assay	7814604	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

chloride channel protein ClC-Ka

chloride channel K1	chloride channel Ka
chloride channel, voltage-sensitive Ka	clC-K1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02760	CLCNKA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Clcnka	NCBI	NCBI:1187

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