NAA16 - N-alpha-acetyltransferase 16, NatA auxiliary subunit Gene
Also Known as NARG1L
Species: Homo sapiens
About NAA16
This gene has 11 transcripts (splice variants), 140 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 4.0), testis (RPKM 2.5) and 25 other tissues.
Summary
Enables ribosome binding activity. Involved in N-terminal protein amino acid acetylation; negative regulation of apoptotic process; and protein stabilization. Located in cytosol. Part of NatA complex. [provided by Alliance of Genome Resources, Apr 2022]
NAA16 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001110798.2 | NP_001104268.1 | N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 3 |
| NM_018527.4 | NP_060997.2 | N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 2 |
| NM_024561.5 | NP_078837.3 | N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
19480662 | GOA |
| enables ribosome binding |
IDA
IDA: Inferred from direct assay
|
19480662 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in N-terminal protein amino acid acetylation |
IDA
IDA: Inferred from direct assay
|
19480662 | GOA |
| involved in negative regulation of apoptotic process |
IMP
IMP: Inferred from mutant phenotype
|
19480662 | GOA |
| involved in protein stabilization |
IMP
IMP: Inferred from mutant phenotype
|
19480662 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of NatA complex |
IDA
IDA: Inferred from direct assay
|
19480662 | GOA |
| part of NatA complex |
IPI
IPI: Inferred from physical interaction
|
19480662 | GOA |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
19480662 | GOA |
NAA16 Protein Structure
TPR_11: TPR repeat (83 - 139)
NARP1: NMDA receptor-regulated protein 1 (187 - 698)
- 0
- 200
- 400
- 600
- 800
- 864 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
N-alpha-acetyltransferase 16, NatA auxiliary subunit |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | NAA16 | MGD | MGI:1914147 |
| Felis catus | NAA16 | VGNC | VGNC:102263 |
| Macaca mulatta | NAA16 | VGNC | VGNC:96716 |
| Bos taurus | NAA16 | VGNC | VGNC:53828 |
| Rattus norvegicus | NAA16 | RGD | RGD:1584324 |
| Canis familiaris | NAA16 | VGNC | VGNC:84245 |
| Others | NAA16 | NCBI |