2. Gene
  3. HECTD3 - HECT domain E3 ubiquitin protein ligase 3 Gene

HECTD3 - HECT domain E3 ubiquitin protein ligase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79654 | Gene type: protein coding

About HECTD3

Cytogenetic location: 1p34.1 Genomic coordinates (GRCh38): 1:45,002,548-45,011,324 (from NCBI)

This gene has 7 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in duodenum (RPKM 25.9), small intestine (RPKM 22.6) and 25 other tissues.

Summary

The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating Enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8. [provided by RefSeq, Dec 2012]

HECTD3 Products(1)

mRNA Protein Name
NM_024602.6 NP_078878.3 E3 ubiquitin-protein ligase HECTD3

HECTD3 Protein Structure

ANAPC10

ANAPC10: Anaphase-promoting complex, subunit 10 (APC10) (247 - 389)

HECT

HECT: HECT-domain (ubiquitin-transferase) (583 - 848)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 861 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase HECTD3

HECT domain containing E3 ubiquitin protein ligase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06109 HECTD3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus HECTD3 VGNC VGNC:29802
Mus musculus HECTD3 MGD MGI:1923858
Rattus norvegicus HECTD3 RGD RGD:1309823
Macaca mulatta HECTD3 VGNC VGNC:73240
Felis catus HECTD3 VGNC VGNC:62784