ZDHHC14 - zinc finger DHHC-type palmitoyltransferase 14 Gene

Also Known as NEW1CP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79683

About ZDHHC14

Cytogenetic location: 6q25.3 Genomic coordinates (GRCh38): 6:157,381,190-157,678,157 (from NCBI)

This gene has 9 transcripts (splice variants), 198 orthologues and 17 paralogues. Ubiquitous expression in brain (RPKM 2.5), endometrium (RPKM 2.3) and 24 other tissues.

Summary

Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC14 Products (2)

mRNA Protein Name
NM_024630.3 NP_078906.2 palmitoyltransferase ZDHHC14 isoform 1
NM_153746.2 NP_714968.1 palmitoyltransferase ZDHHC14 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyltransferase activity IDA
IDA: Inferred from direct assay
23034182 GOA
Biological Process GO Annotation Evidence References Source
involved in peptidyl-L-cysteine S-palmitoylation IMP
IMP: Inferred from mutant phenotype
27481942 GOA
involved in protein palmitoylation IDA
IDA: Inferred from direct assay
23034182 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16647879 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZDHHC14 Protein Structure

DHHC

DHHC: DHHC palmitoyltransferase (109 - 287)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 488 a.a.
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC14

  • DHHC domain-containing cysteine-rich protein 14

Related Diseases

Diseases Alias
Chromosome 6q24-Q25 Deletion Syndrome

  • Chromosome 6q25-Q25 Deletion Syndrome

  • 6q25 Microdeletion Syndrome

  • Monosomy 6q25

  • Del(6)(Q25)
Trichothiodystrophy 3, Photosensitive

  • TTD3

  • Trichothiodystrophy, Complementation Group A

  • Ttda

  • Photosensitive Trichothiodystrophy 3

  • Trichothiodystrophy Complementation Group A
Coffin-Siris Syndrome 1

  • Coffin-Siris Syndrome

  • Fifth Digit Syndrome

  • Css

  • CSS1

  • Mrd12

  • Mental Retardation, Autosomal Dominant 12

  • Hhid

  • Dwarfism-Onychodysplasia

  • Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features

  • Autosomal Dominant Mental Retardation 12

  • Short Stature-Onychodysplasia.

  • Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx

  • Mental Retardation With Hypoplastic Fifth Fingernails And Toenails

  • Short Stature-Onychodysplasia

  • Coffin-Siris Syndrome, Type 1

  • Mental Retardation, Autosomal Dominant, Type 12
Lung Acinar Adenocarcinoma

  • Acinar Adenocarcinoma Of The Lung
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16014 ZDHHC14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ZDHHC14 VGNC VGNC:67203
Rattus norvegicus ZDHHC14 RGD RGD:1565877
Mus musculus ZDHHC14 MGD MGI:2653229
Bos taurus ZDHHC14 VGNC VGNC:37129
Macaca mulatta ZDHHC14 VGNC VGNC:82270
Canis familiaris ZDHHC14 VGNC VGNC:48580
Others ZDHHC14 NCBI