NSUN7 - NOP2/Sun RNA methyltransferase family member 7 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79730

About NSUN7

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:40,749,955-40,811,184 (from NCBI)

This gene has 7 transcripts (splice variants) and 213 orthologues. Broad expression in testis (RPKM 10.8), thyroid (RPKM 2.4) and 19 other tissues.

Summary

Predicted to enable RNA binding activity and methyltransferase activity. Predicted to be involved in methylation. Predicted to act upstream of or within flagellated sperm motility and sperm mitochondrion organization. [provided by Alliance of Genome Resources, Apr 2022]

NSUN7 Products (2)

mRNA Protein Name
NM_001330648.3 NP_001317577.1 putative methyltransferase NSUN7 isoform 2
NM_024677.6 NP_078953.4 putative methyltransferase NSUN7 isoform 1

NSUN7 Protein Structure

Methyltr_RsmB-F

Methyltr_RsmB-F: 16S rRNA methyltransferase RsmB/F (414 - 455)

  • 0
  • 200
  • 400
  • 600
  • 718 a.a.
Protein Preferred Names Protein Names

putative methyltransferase NSUN7

  • NOL1/NOP2/Sun domain family member 7

Related Diseases

Diseases Alias
Dubowitz Syndrome

  • Dubowitz'S Syndrome

  • Dwarfism-Eczema-Peculiar Facies Syndrome

  • Intrauterine Growth Restriction, Short Stature, Microcephaly, Mild Intellectual Disability With Behavior Problems, Eczema, And Unusual And Distinctive Faci
Cardiomyopathy, Familial Restrictive, 1

  • RCM1

  • Restrictive Cardiomyopathy 1

  • Rcm

  • Familial Restrictive Cardiomyopathy 1

  • Cardiomyopathy, Familial Restrictive 1

  • Cardiomyopathy, Restrictive, Familial, Type 1

  • Rcm-1
Autosomal Recessive Intellectual Developmental Disorder

  • Mental Retardation, Autosomal Recessive

  • Autosomal Recessive Mental Retardation

  • Autosomal Recessive Non-Syndromic Mental Retardation

  • Autosomal Recessive Non-Syndromic Intellectual Disability
Williams-Beuren Syndrome

  • Williams Syndrome

  • WBS

  • Wms

  • Deletion 7q11.23

  • Monosomy 7q11.23

  • Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb

  • Fanconi Schlesinger Syndrome

  • Beuren Syndrome

  • Elfin Facies Syndrome

  • Elfin Facies With Hypercalcemia

  • Hypercalcemia-Supravalvar Aortic Stenosis

  • Ws
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09606 NSUN7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21672 Nsun7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28190 Nsun7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NSUN7 VGNC VGNC:75463
Rattus norvegicus NSUN7 RGD RGD:1310137
Mus musculus NSUN7 MGD MGI:1918168
Bos taurus NSUN7 VGNC VGNC:32288
Canis familiaris NSUN7 VGNC VGNC:43993
Felis catus NSUN7 VGNC VGNC:63896
Others NSUN7 NCBI