ZFAND1 - zinc finger AN1-type containing 1 Gene
Species: Homo sapiens
About ZFAND1
This gene has 25 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 23.7), ovary (RPKM 15.6) and 25 other tissues.
Summary
Enables Proteasome binding activity. Involved in cellular response to arsenite ion; positive regulation of intracellular protein transport; and stress granule disassembly. Located in cytoplasmic stress granule. [provided by Alliance of Genome Resources, Apr 2022]
ZFAND1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001170796.1 | NP_001164267.1 | AN1-type zinc finger protein 1 isoform b |
| NM_001170797.2 | NP_001164268.1 | AN1-type zinc finger protein 1 isoform c |
| NM_024699.3 | NP_078975.2 | AN1-type zinc finger protein 1 isoform a |
ZFAND1 Protein Structure
zf-AN1: AN1-like Zinc finger (10 - 47)
zf-AN1: AN1-like Zinc finger (64 - 102)
- 0
- 100
- 200
- 268 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
AN1-type zinc finger protein 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Inclusion Body Myopathy With Early-Onset Paget Disease Of Bone With Or Without Frontotemporal Dementia 1 |
|
|
| Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | ZFAND1 | VGNC | VGNC:50112 |
| Felis catus | ZFAND1 | VGNC | VGNC:67224 |
| Canis familiaris | ZFAND1 | VGNC | VGNC:48599 |
| Mus musculus | ZFAND1 | MGD | MGI:1913611 |
| Macaca mulatta | ZFAND1 | VGNC | VGNC:79551 |
| Rattus norvegicus | ZFAND1 | RGD | RGD:1309519 |
| Others | ZFAND1 | NCBI |