SNX22 - sorting nexin 22 Gene
Species: Homo sapiens
About SNX22
This gene has 7 transcripts (splice variants), 188 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 48.1), placenta (RPKM 36.5) and 25 other tissues.
Summary
The protein encoded by this gene is a sorting nexin that is found in the cytoplasm, where it interacts with membrane-bound phosphatidylinositol 3-phosphate. The encoded protein may play a role in intracellular trafficking. Two transcript variants, one protein-coding and the Other not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
SNX22 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_024798.3 | NP_079074.2 | sorting nexin-22 |
SNX22 Protein Structure
PX: PX domain (18 - 105)
- 0
- 100
- 193 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sorting nexin-22 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Osteogenesis Imperfecta, Type Ix |
|
|
| Brittle Bone Disorder |
|
|
| Fibrillary Astrocytoma |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | SNX22 | RGD | RGD:1305042 |
| Bos taurus | SNX22 | VGNC | VGNC:35102 |
| Mus musculus | SNX22 | MGD | MGI:2685966 |
| Macaca mulatta | SNX22 | VGNC | VGNC:77720 |
| Canis familiaris | SNX22 | VGNC | VGNC:46632 |
| Others | SNX22 | NCBI |