Pofut2 - protein O-fucosyltransferase 2 Gene

Also Known as FUT13; C21orf80; 2310011G23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80294

Summary

Enables fucosyltransferase activity. Acts upstream of or within several processes, including fucosylation; mesoderm formation; and regulation of epithelial to mesenchymal transition. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Orthologous to human POFUT2 (protein O-fucosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Pofut2 Products (1)

mRNA Protein Name
NM_030262.3 NP_084538.2 GDP-fucose protein O-fucosyltransferase 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fucosyltransferase activity IDA
IDA: Inferred from direct assay
20637190 MGI
enables peptide-O-fucosyltransferase activity IDA
IDA: Inferred from direct assay
20637190 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within fucosylation IMP
IMP: Inferred from mutant phenotype
20637190 MGI
acts upstream of or within mesoderm formation IMP
IMP: Inferred from mutant phenotype
20637190 MGI
involved in protein O-linked fucosylation IDA
IDA: Inferred from direct assay
20637190 MGI
acts upstream of or within regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
20637190 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20637190 MGI
Cellular Component GO Annotation Evidence References Source
is active in endoplasmic reticulum membrane IMP
IMP: Inferred from mutant phenotype
20637190 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GDP-fucose protein O-fucosyltransferase 2

  • O-FucT-2

  • peptide-O-fucosyltransferase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10812 POFUT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pofut2 NCBI NCBI:23275