Pacsin3 - protein kinase C and casein kinase substrate in neurons 3 Gene

Also Known as 4921507A02Rik; 6330413E15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80708

Summary

Enables Calcium Channel Inhibitor activity; cytoskeletal protein binding activity; and lipid binding activity. Involved in negative regulation of calcium ion transport and plasma membrane tubulation. Acts upstream of or within negative regulation of endocytosis. Located in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human PACSIN3 (protein kinase C and Casein Kinase substrate in neurons 3). [provided by Alliance of Genome Resources, Apr 2022]

Pacsin3 Products (4)

mRNA Protein Name
NM_001289677.1 NP_001276606.1 protein kinase C and casein kinase II substrate protein 3
NM_001289678.1 NP_001276607.1 protein kinase C and casein kinase II substrate protein 3
NM_028733.4 NP_083009.1 protein kinase C and casein kinase II substrate protein 3
NM_030880.3 NP_112019.2 protein kinase C and casein kinase II substrate protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel inhibitor activity IMP
IMP: Inferred from mutant phenotype
18174177 MGI
enables cytoskeletal protein binding IDA
IDA: Inferred from direct assay
11082044 MGI
enables lipid binding IDA
IDA: Inferred from direct assay
22573331 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11082044 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of calcium ion transport IMP
IMP: Inferred from mutant phenotype
18174177 MGI
acts upstream of or within negative regulation of endocytosis IDA
IDA: Inferred from direct assay
11082044 MGI
involved in negative regulation of endocytosis IMP
IMP: Inferred from mutant phenotype
16627472 MGI
involved in plasma membrane tubulation IDA
IDA: Inferred from direct assay
22573331 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11082044 MGI
NOT located in trans-Golgi network IDA
IDA: Inferred from direct assay
11082044 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein kinase C and casein kinase II substrate protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09959 PACSIN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pacsin3 NCBI NCBI:29763